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    Prism (PTSD)

    Prism — Clinical Research Overview

    A review of the clinical research behind Prism for PTSD, including the rates of clinically significant improvement and remission seen in the study.

    About this video

    SAINT® (Stanford Neuromodulation Therapy) is an FDA-cleared, fMRI-guided form of TMS completed over five consecutive days. It is cleared for adults with major depressive disorder who have not improved enough on antidepressant medication in the current episode.

    In a small randomized trial, 11 of 14 people receiving active treatment reached remission at the four-week assessment, compared with 2 of 15 receiving sham treatment. Individual results may vary; a five-day treatment course does not guarantee remission in five days.

    Sources: Cole et al., American Journal of Psychiatry 2020;177:716-726 and 2022;179(2):132-141. This video is educational and is not medical advice. Talk to a qualified clinician about whether SAINT is appropriate for you. If you are in crisis, call or text 988.

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