SAINT® TMS Explained: A 5-Day, fMRI-Guided Depression Treatment
What SAINT® is, how it differs from standard TMS, and what research shows. SAINT® is an FDA-cleared, fMRI-guided form of TMS completed in five days for adults with major depressive disorder who have not improved on antidepressants.
About this video
SAINT® (Stanford Neuromodulation Therapy) is an FDA-cleared, fMRI-guided form of TMS completed over five consecutive days. It is cleared for adults with major depressive disorder who have not improved enough on antidepressant medication in the current episode.
In a small randomized trial, 11 of 14 people receiving active treatment reached remission at the four-week assessment, compared with 2 of 15 receiving sham treatment. Individual results may vary; a five-day treatment course does not guarantee remission in five days.
Sources: Cole et al., American Journal of Psychiatry 2020;177:716-726 and 2022;179(2):132-141. This video is educational and is not medical advice. Talk to a qualified clinician about whether SAINT is appropriate for you. If you are in crisis, call or text 988.
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