What Happens If Antidepressants Don't Work?
If you've tried antidepressants and are still experiencing depression, you are not out of options. There are treatments developed specifically for this situation.
Want to know if SAINT® is right for you?
Tell us about your treatment history and symptoms. A consultation is an evaluation, not a commitment — and it starts with your story.
It's More Common Than You Think
About a third of people with depression don't get adequate relief from oral antidepressants. That's not a small unlucky minority — it's a known limitation of how those medications work.
There's a Name for It
Depression that hasn't responded adequately to one or more antidepressant trials is called treatment-resistant depression. It sounds like a judgment, but it isn't. It's a category that exists because this situation is common enough to need one.
Curious whether you'd qualify?
If you've tried medication and you're still not yourself, you may be a candidate for SAINT®. Our team will give you a straight answer.
Other Mechanisms Exist
Treatments like TMS, SAINT®, and SPRAVATO® work through different mechanisms than oral antidepressants. That's the whole reason they exist — for people the standard approach hasn't reached.
What to Do Next
If you've tried multiple antidepressants without adequate relief, a consultation can help you understand what other options may be appropriate. You don't need to have everything figured out before calling.
Frequently Asked Questions
How many antidepressants do I need to try before other options?
Does trying other treatments mean giving up on medication?
Ready to talk to someone?
The hardest part is usually the first phone call. Everything after that is a series of small, defined steps.
You Don't Have to Figure This Out Alone
If antidepressants haven't worked, there are other approaches. Speak with our team about what may be appropriate.