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    Evidence-Based Medicine

    Supplemental Research & Clinical Evidence

    Our clinical protocols are firmly rooted in peer-reviewed science published in top medical journals including The American Journal of Psychiatry, JAMA Psychiatry, and Nature Medicine.

    Key Peer-Reviewed Clinical Publications

    Click below to read summaries of landmark clinical studies supporting our treatments.

    Cole EJ, et al. American Journal of Psychiatry (2020 & 2022)

    Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®)

    Double-blind randomized controlled trial demonstrating 79% remission rates in severe treatment-resistant depression following 5 days of accelerated iTBS.

    Fruchter E, et al. Psychiatry Research (2024)

    Prism™ Amygdala-Derived EEG-fMRI Neurofeedback for PTSD

    Multi-center clinical study showing 67% significant symptom reduction and 32% remission in chronic PTSD patients 3 months post-treatment.

    George MS, et al. Archives of General Psychiatry (2010)

    FDA Approval & Efficacy of Transcranial Magnetic Stimulation (TMS)

    Pivotal multi-site trial establishing efficacy of daily left prefrontal TMS in unmedicated major depressive disorder.

    Zarate CA Jr, et al. Archives of General Psychiatry (2006)

    Rapid Antidepressant Effects of IV Ketamine Infusion

    Landmark double-blind trial demonstrating rapid and robust antidepressant response within hours of a single low-dose IV ketamine infusion.

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    Let's find your path forward — together

    Reaching out is the hardest part, and you've already started. Tell us a little about yourself and our compassionate care team will reach out within one business day to answer your questions, verify your insurance, and help you take the next step — at no cost and no obligation.

    Two pathways to care: self-pay offers the fastest access (most patients start within days, with appointments available seven days a week), or we accept Blue Cross Blue Shield in select states and the BCBS Federal Employee Program in select states. We'll help you find the right path for your situation.

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